Polynucleotides in Alderley Edge, Cheshire
Polynucleotides are one of the most clinically advanced treatments in aesthetics. They work at a cellular level, stimulating your skin’s own repair and regeneration mechanisms in ways that other injectables cannot. The result is genuine improvement in skin quality, better tone, better texture, fewer fine lines, and improved firmness.
Polynucleotide Prices
- 1 Session: from £150
- 2 Sessions: from £275
- 3 Sessions: from £390
Most clients need three to four sessions for an initial course. A free consultation is the starting point.
TREATMENT TIME
30 to 45 minutes per session
DOWNTIME
Minimal
LASTS FOR
3 to 6 months
PRICE
From £150 per session
COMMON SIDE EFFECTS
Mild redness and swelling at injection sites. Settles within 24 to 48 hours.
How Polynucleotides Work
Polynucleotides (also known as PDRN) are chains of DNA fragments derived from purified salmon DNA. When injected into the skin, they bind to specific receptors that activate your body’s tissue repair processes. Collagen production increases. Blood supply to the treated area improves. Dead or damaged cells are replaced more efficiently.
The overall effect is skin that genuinely regenerates, not just temporarily plumped. Most clients notice visible improvement after their second session, with the full result apparent after completing the initial course.
What Can Polynucleotides Treat?
Polynucleotides are particularly effective for fine lines and surface dehydration, uneven skin tone and pigmentation, crepey or thinning skin, under-eye hollowing and dark circles, acne scarring and post-inflammatory marks, and general loss of skin quality.
A course typically involves three to four sessions spaced two to three weeks apart, followed by maintenance every three to six months. Each session takes 30 to 45 minutes with minimal downtime.
- Reduce the appearance of fine lines and deeper wrinkles - Softens areas such as forehead lines, frown lines between the brows, and crow’s feet around the eyes.
- Help prevent new wrinkles from forming - By relaxing targeted muscles, anti-wrinkle treatment limits repetitive movements that create new creases over time.
- Fit into your schedule - Most appointments take under 30 minutes in our Bracknell clinic, so you can get back to your day without downtime.
- Deliver natural-looking results - We focus on maintaining natural facial movement while reducing unwanted lines.
- Boost confidence - Many clients find they feel more positive about their appearance after treatment.
- Provide a personalised approach - Every treatment is tailored to your face shape, skin, and goals to ensure results that complement your features.
Polynucleotides FAQs
How long before I see results?
Most clients see their first noticeable improvement after the second session, typically at four to six weeks. Full results from an initial course appear at eight to twelve weeks.
Are polynucleotides safe?
Yes. PDRN has an extensive clinical safety record spanning over 30 years of use in regenerative medicine. Side effects are mild and temporary.
How is this different from Profhilo?
Profhilo hydrates and stimulates collagen via hyaluronic acid. Polynucleotides trigger cellular repair and regeneration through a different biological mechanism. They target different aspects of skin ageing and work well together.
Can I combine polynucleotides with other treatments?
Yes. Polynucleotides combine particularly well with Profhilo, Sculptra, microneedling, and skin boosters.