Profhilo Bracknell
Profhilo is one of the most popular skin remodelling treatments, using ultra-pure hyaluronic acid to deeply hydrate, firm and remodel the skin. At SIX1 Aesthetics in Bracknell, we use Profhilo to address skin laxity, loss of firmness and overall skin quality in the face, neck and hands.
PROCEDURE TIME
30-45 Minutes
DOWNTIME
Minimal
LASTS FOR
6-12 months
PRICE
From £150 per session

COMMON SIDE EFFECTS
Redness, mild swelling, bruising
What Is Profhilo?
Profhilo is an injectable treatment containing one of the highest concentrations of hyaluronic acid available. Unlike traditional dermal fillers, it diffuses through the tissue to stimulate four different types of collagen and elastin, improving skin quality at a deep level and delivering intense hydration.
Benefits of Profhilo
Profhilo delivers results that improve the quality and tone of skin rather than changing its shape. It is ideal for clients who want to look refreshed and naturally more youthful without altering their features.
Key benefits include:
- Improved skin firmness and elasticity
- Deep hydration and glow
- Reduction in fine lines and crepiness
- Skin remodelling without volume addition
- Suitable for face, neck, decolletage and hands
- Only two sessions required in the primary course
- Stimulates collagen and elastin production
- Repairs and regenerates skin tissue at a cellular level
- Reduces fine lines and improves skin laxity
- Effective for under-eye circles and crepey skin
- Cumulative results that build over time
Profhilo is delivered in two sessions, four weeks apart. Results begin to show within four weeks of the first session and continue to improve after the second.
How Profhilo Treatment Works
Profhilo is injected via bio aesthetic points — five specific injection sites per side of the face — allowing the product to spread evenly through the tissue. Each session takes around 20 to 30 minutes.
Consultation and skin analysis
We start with a full consultation to discuss your skin concerns and assess the areas you want to treat. This lets us design a personalised treatment course tailored to your goals and skin type.
Application of numbing cream
A topical numbing cream is applied to the treatment area to ensure your comfort throughout the procedure.
Precise Profhilo injections
Using a fine needle, Profhilo is placed at specific anatomical points that allow the product to diffuse naturally through the surrounding tissue. This minimises injection points while ensuring even distribution and improvement in skin quality across the full treatment area.
Course of treatments for best results
Polynucleotides work cumulatively. We recommend a course of three to four sessions to achieve the best results, with maintenance treatments every six to twelve months to sustain and build on your improvements.
How Long Does Profhilo Last?
Profhilo results typically last six to nine months after your initial two-session course. Many clients choose a single maintenance session every six months to sustain their results. The treatment is cumulative and repeat sessions often deliver improved results over time.
Profhilo Aftercare
After your Profhilo treatment, you may notice small raised bumps at the injection sites that resolve within a few hours. Avoid touching the treated area, intense exercise, alcohol, saunas and direct sun exposure for 24 hours. Most clients resume normal activities immediately.
Why Choose SIX1 Aesthetics
At SIX1 Aesthetics in Bracknell, we use authentic Profhilo product and expert technique to ensure safe and effective results. We see clients from Bracknell, Wokingham, Reading, Camberley and across Berkshire. Book a consultation today.

Profhilo Treatments
| Polynucleotides | Procedure time | Downtime | Lasts For | Price (From) | Common Side Effects |
|---|---|---|---|---|---|
| Single PN Session | 30-45 minutes | Minimal | Builds over time | From £150 | Redness, mild swelling, bruising |
| PN Course (3 sessions) | 30-45 minutes | Minimal | 6-12 months | From £320 | Redness, mild swelling, bruising |
Profhilo FAQ's
What are polynucleotides?
Polynucleotides are long chains of DNA molecules that stimulate the skin's natural repair and regeneration processes. When injected into the skin, they activate fibroblasts — the cells that produce collagen and elastin — improving skin quality, firmness, and texture from the inside out.
How are polynucleotides different from other injectables?
Unlike hyaluronic acid fillers or skin boosters, polynucleotides work by regenerating skin tissue rather than filling or hydrating directly. They trigger collagen production and tissue repair at a cellular level, delivering results that build progressively over a course of treatment.
How many sessions do I need?
Most clients benefit from a course of three to four sessions, spaced two to four weeks apart. Results build gradually, and the full effect is usually visible a few months after completing the course. Maintenance treatments every six to twelve months help sustain your results.
Are polynucleotides the same as PDRN?
PDRN (polydeoxyribonucleotide) is a specific type of polynucleotide with a particularly strong ability to stimulate tissue regeneration. The terms are sometimes used interchangeably, but polynucleotides encompasses a range of similar products. All work by activating the skin's natural repair processes.
Does polynucleotide treatment hurt?
Numbing cream is applied before treatment to minimise discomfort. Most clients find the procedure comfortable, though you may feel a slight stinging sensation during injections. Any discomfort is brief and very manageable.
How soon will I see results?
Most clients notice improvements in skin texture and hydration after two to three sessions. The full regenerative effect becomes visible over several months as collagen production increases. Polynucleotides are a gradual treatment — a full course delivers the best results.
Are polynucleotides suitable for sensitive skin?
Polynucleotides are generally well-tolerated, including by clients with sensitive skin. Because they work in harmony with the body's own biology, adverse reactions are uncommon. We will assess your skin and medical history at your consultation to confirm suitability.
Can polynucleotides treat under-eye dark circles?
Yes. Polynucleotides are particularly effective in the under-eye area, improving the quality of delicate skin, reducing dark circles, and addressing crepiness. Multiple sessions are typically needed for the best results in this area.
Can polynucleotides be combined with other treatments?
Yes, polynucleotides work well alongside many other aesthetic treatments, including anti-wrinkle injections, dermal fillers, and Profhilo. A combined approach can address multiple concerns at once. We will design a tailored plan at your consultation.
Who is not suitable for polynucleotide treatments?
Polynucleotide treatments are not recommended for those who are pregnant or breastfeeding, have a known allergy to fish or salmon, have active skin infections in the treatment area, or have certain autoimmune conditions. We will review your medical history at consultation.
