Profhilo treatment is an injectable skin booster that hydrates and firms the skin using one of the highest concentrations of hyaluronic acid available. Unlike a dermal filler, it does not add volume to one spot. Instead it spreads under the skin and prompts your body to produce fresh collagen and elastin, a process called bio-remodelling. The result is firmer, more hydrated, better-quality skin with a natural glow. Most people have 2 sessions about 4 weeks apart, and results typically last around 6 months. It suits people who want healthier, tighter-looking skin rather than a change in shape, and it is popular for the face, neck and hands.
On this page
- What is Profhilo?
- How does Profhilo work?
- Profhilo vs filler vs polynucleotides
- What happens during treatment?
- When will I see results and how long do they last?
- Where can I get Profhilo near me?
- Frequently asked questions
What is Profhilo?
Profhilo is an injectable made from highly concentrated hyaluronic acid, a substance your skin produces naturally to stay plump and hydrated. It sits in a category often called skin boosters or bio-remodelling treatments. The important thing to understand is that it is not a traditional filler. A filler is designed to add volume and shape to a specific area, like the cheeks or lips. Profhilo is designed to improve the overall quality of the skin: hydration, firmness and that healthy bounce that fades with age.
It is made through a heat-based stabilising process that lets the product release slowly and spread smoothly under the skin, rather than staying in one place.
A natural way to hydrate and firm tired, crepey skin. We assess your skin and tell you honestly whether it is the right fit.
Book a Consultation →How does Profhilo work?
Once injected, Profhilo does two things at once. First, the high concentration of hyaluronic acid draws in and holds water, which hydrates the skin from within and gives an immediate freshness over the following days. Second, and more importantly for the longer term, it gently stimulates your fibroblasts, the cells that produce collagen and elastin. These are the proteins that keep skin firm and springy, and we make less of them as we age.
The product stays active in the skin for around 28 days, slowly releasing and prompting the skin to rebuild. Because this is a biological process, the best results build over several weeks rather than appearing on the day. For general guidance on choosing a qualified practitioner for any injectable treatment, the NHS guidance on injectable treatments is a sensible read.
Profhilo vs filler vs polynucleotides
These three get mixed up a lot because they are all injectables, but they do different jobs. The table makes it clear.
| Feature | Profhilo | Dermal filler | Polynucleotides |
|---|---|---|---|
| Main job | Hydrate and firm overall skin | Add volume and shape | Repair and renew skin quality |
| Made from | Hyaluronic acid | Hyaluronic acid (firmer gel) | Purified DNA fragments |
| Best for | Crepey, tired, lax skin | Lips, cheeks, defined lines | Under-eyes, fragile skin |
| Typical course | 2 sessions, 4 weeks apart | Often 1 | Around 3 sessions |
| Results last | Around 6 months | 6 to 18 months | 6 to 9 months |
Profhilo and polynucleotides both improve skin quality and are sometimes confused. If you want a fuller comparison, read our guide to polynucleotides treatment. Your practitioner will help you choose the right one for your skin.
What happens during treatment?
A session is quick and comfortable. Here is the usual sequence:
- A consultation to assess your skin and confirm Profhilo is right for your concern.
- The skin is cleaned and the product is placed through a small number of injection points.
- The product is left to spread naturally under the skin.
- You are given simple aftercare advice for the next day or two.
The session itself usually takes around 30 minutes. You may have small raised bumps at the injection points that settle within a day, and most people return to normal activities the same day.
When will I see results and how long do they last?
Many people notice improved hydration and a subtle glow within the first week. The firmer, smoother result builds over the following weeks, and is usually best seen about 4 weeks after the second session. From there, results typically last around 6 months. Many people then choose a single maintenance session every 6 months to keep the effect going. As always, results vary from person to person, and we never promise a specific outcome.
Where can I get Profhilo near me?
We offer Profhilo at our clinic in Bracknell, Berkshire, and you can also book Profhilo and other skin boosters at our Alderley Edge clinic in Cheshire. The best first step is always a consultation, so we can look at your skin in person and recommend the right approach.
Profhilo and other skin boosters at our Alderley Edge clinic, tailored to your skin in a one to one consultation.
Book a Consultation →Frequently asked questions
Does Profhilo hurt?
Most people find it very manageable. It is placed through a small number of injection points and the treatment is quick. Any tenderness or small bumps usually settle within a day.
How many sessions will I need?
The standard course is 2 sessions about 4 weeks apart. After that, many people have a single maintenance session every 6 months. Your exact plan is agreed at your consultation.
Is Profhilo a filler?
No. It is made from hyaluronic acid like many fillers, but it is designed to hydrate and firm the whole area rather than add volume or shape to one spot.
Is there any downtime?
Very little. You may have small raised bumps at the injection points for a few hours, and mild redness. Most people carry on with their day as normal.
Profhilo or polynucleotides, which is better?
Neither is simply better. They suit different concerns. Profhilo focuses on hydration and firmness, while polynucleotides focus on repairing fragile or tired skin such as the under-eyes. A consultation is the best way to decide.
Want firmer, healthier-looking skin?
Book a one to one consultation and we will assess your skin honestly and tell you whether Profhilo is the right fit for you.
Book Your Consultation →Bracknell, Berkshire and Alderley Edge, Cheshire. Same-week appointments often available.
